Skip to content
exterior of Paterno Library

Drosophila Genetics

How to find: Information on basic mutations in DROSOPHILA

General Resources

Check the CAT for books on Drosophila or use the following:

Encyclopedia of Genetics.  Knight, J.A., editor. 1999. 2 Volumes. Pasadena, CA: Salem Press.

  • In Print
  • section on Drosophila (volume 1 pp.172-178) gives nice summary of history of use as a model for genetics

Encyclopedia of Genetics. Brenner, Sydney and Miller, Jeffrey H., editors. 2002. 4 Volumes. San Diego, CA: Academic.

  • Online
  • In Print 
  • article on Thomas Morgan mention white eye; article on Drosophila gives good introducation to use of fruit flies as a model for genetics; article on unequal crossing-over discusses bar eye.

Drosophila Guide : a guide to introductory studies of the genetics and cytology of Drosophila melanogaster, with an appendix containing a series of experiments to be conducted by the beginning student.  Demerec, M. and Kaufmann, B.P. 1945.  Washington DC: Carnegie Institution of Washington.

  • In Print
  • appendix describes bar, curly, white and other mutations

Genetic Variations of Drosophila Melanogaster.  Lindsley, D.L. and Grell, E.H. 1968. Carnegie Institution of Washington Publication No. 627. Washington: Carnegie Institution of Washington.

  • In Print
  • lists mutations and gives references to the articles where these mutants were originally described (pp. 22-23, 65, 266-267)

Drosophila : a laboratory handbook. Ashburner, M., Golic, K.G. and Hawley, R.S. 2005. 2nd Edition. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.

  • In Print 
  • lists books to peruse for information about various aspects of research on Drosophila (pp. 6-13); most mutations discussed are modern variants

Encyclopedia of Life Sciences.  Fullerlove, Gina, publishing director. 2002.  New York: Nature Publishing Group.

  • In Print
  • article on Thomas Morgan mentions white eye;
  • article on Drosophila evolutionary genetics discusses the use of fruit flies as model organisms in genetics

Experiments in Genetics with Drosophila.  Strickberger, Monroe W. 1962. New York: Wiley.

  • In Print
  • Copy also available at the Life Sciences Library Reference Desk (4th floor Paterno, University Park) 
  • appendices give descriptions of mutations, mutations listed according to affected parts, and a linkage map

Newer articles on more recent mutations can be found in Biological Abstracts by searching Drosophila AND genetics (newest results are shown first; NOTE: many results are likely to be NOT owned by PSU).

Some older articles on simple mutations, such as White Eye, Bar Eye and Curly Wing can be found in JSTOR by using the ADVANCED SEARCH. Search Drosophila and limit your search DATES to 1900 through 1925. Many hundreds of records will be retrieved, so you may consider just using those listed on this page under their specific mutations.

There are other online databases from the Drosophila research community.

The best known is the database Flybase where you can search by gene, such as Bar, and then see a map of the gene, list of references to that mutation, etc.

Bar Eye

Encyclopedia of Genetics. Brenner, Sydney and Miller, Jeffrey H., editors. 2002. 4 Volumes. San Diego, CA: Academic.

A Dictionary of Genetics. King, R.C. and Stansfield, W.D., editors. 2002. 6th Edition. New York: Oxford University Press.

  • Online (select "biological sciences" and then "a dictionary of genetics")
  • In Print
  • definition of Bar eye mutant (p.39) clearly states its sex-linked dominant character

An Introduction to Genetics. Sturtevant, A.H. and Beadle, G.W. 1939.  Philadelphia: W.B. Saunders Co.

  • In Print
  • Copy also available at the Life Sciences Library Reference Desk (4th floor Paterno, University Park) 
  • chapter 2 on sex-linkage discusses bar-eye

Sex-Linked Inheritance in Drosophila. Morgan, T.H. and Bridges, C.B. 1916.  Carnegie Institution of Washington Publication No. 237. Washington DC: Carnegie Institution of Washington.

  • In Print 
  • Copy also available at the Life Sciences Library Reference Desk (4th floor Paterno, University Park) 
  • discusses white eye and bar eye

Tice SC. 1914. A New Sex-Linked Character in Drosophila. Biological Bulletin 26:221-230.

  • Online
  • Copy also available at the Life Sciences Library Reference Desk (4th floor Paterno, University Park)
  • original article describing bar-eye mutation

Sturtevant AH, Morgan TH. 1923. Reverse Mutation of the Bar Gene Correlated with Crossing Over. Science 57(1487):746-747.

  • Online
  • Copy also available at the Life Sciences Library Reference Desk (4th floor Paterno, University Park)
  • mentions bar-eye mutation

Morgan, T.H., Bridges, C.B., and Sturtevant, A.H. 1925. The Genetics of Drosophila. Bibliographia Genetica 2:1-262.

  • PSU copy at the Annex.  Request via ILLiad (select annexed items form)
  • Copy also available at the Life Sciences Library Reference Desk (4th floor Paterno, University Park)
  • pages 29-32 mention bar; chapter 22 lists and describes mutant charaters of Drosophila; literature sections gives plenty of suggestions for further reading

Elens AA. 1965. Studies of Selective Mating Using the Sex-Linked Mutants White and Bar of Drosophila Melanogaster. Experientia 21(10):594-595.

  • Online
  • Copy also available at the Life Sciences Library Reference Desk (4th floor Paterno, University Park)
  • mentions bar and white eye are sex-linked mutations
White Eye

Encyclopedia of Genetics. Brenner, Sydney and Miller, Jeffrey H., editors. 2002. 4 Volumes. San Diego, CA: Academic.

Encyclopedia of Life Sciences.  Fullerlove, Gina, publishing director. 2002.  New York: Nature Publishing Group.

  • In Print
  • article on Thomas Morgan mentions white eye;

Sex-Linked Inheritance in Drosophila. Morgan, T.H. and Bridges, C.B. 1916.  Carnegie Institution of Washington Publication No. 237. Washington DC: Carnegie Institution of Washington.

  • In Print 
  • Copy also available at the Life Sciences Library Reference Desk (4th floor Paterno, University Park) 
  • discusses white eye and bar eye

Morgan TH. 1910. Sex Limited Inheritance in Drosophila. Science 32(812):120-122.

  • Online
  • Copy also available at the Life Sciences Library Reference Desk (4th floor Paterno, University Park)
  • original article describing white eye mutants

Morgan TH. 1910. The Method of Inheritance of Two Sex-Linked Characters in the Same Animal. Proceedings of the Society for Experimental Biology and Medicine 8:17-19.

  • PSU copy at the Annex.  Request via ILLiad (select annexed items form)
  • Copy also available at the Life Sciences Library Reference Desk (4th floor Paterno, University Park)
  • mentions the sex linkage of white eye mutation

Morgan TH. 1912. The Explanation of a New Sex Ratio in Drosophila. Science 36(934):718-719.

  • Online
  • Copy also available at the Life Sciences Library Reference Desk (4th floor Paterno, University Park)
  •  mentions sex linkage of white eye mutation

Lancefield DE. 1918. Three Mutations in Previously Known Loci. American Naturalist 52(616/617):264-269.

  • Online
  • Copy also available at the Life Sciences Library Reference Desk (4th floor Paterno, University Park)
  • mentions white eye mutation
Curly Wing

Ward L. 1923. The Genetics of Curly Wing in Drosophila. Another Case of Balanced Lethal Factors. Genetics 8:276-300.

  • Online
  • Copy also available at the Life Sciences Library Reference Desk (4th floor Paterno, University Park)
  • original article describing curly wing mutation

Ramel C, Valentin J. 1965. Interchromosomal Effects of the Curly Inversion on Crossing-Over in Drosophila Melanogaster. Hereditas 54:307-313.

  • In Print
  • Copy also available at the Life Sciences Library Reference Desk (4th floor Paterno, University Park)
  • mentions curly wing mutation on chromosome 2

Search


Contact

 Life Sciences Library
408 Paterno
University Park, PA 16802
814-865-7056
FInd us on Facebook

Staff Directory
Intranet (Staff Only)

Get Help